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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1002800def844031d5e27ba87fc3b26e3f4c071f7afe47a9e37ca38c6f1802ae' 
  AND token = 'x5Oapgi7nKDIPoQ7eRaUJ2zYDreYhcn2AhoHwWXBaoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}