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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd18dac654bae381f5f9941bb6f4103bdb4fdc39802e0fa7f4c9a44f36e56635f' 
  AND token = 'uQw/6qpus/Zx6rCRRKSDyAyw5LOaECkpcKjnR+HL9Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}