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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3af7cd8aa13b3b233ae878110a53750bab25b281cb91e47403286762b8807a' 
  AND token = 'S0CuU49ymyfwchrIxZ1Ysa66g3Xt2DKHL3fjF4RqNc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}