SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c460c60afcea1ea61356431e2d0639f2f3fa640b2f1cb23b11ea7f4f8c783aff' 
  AND token = 'XI1pV9GoCWkQyW3F7VG4STmTBDOKlyUZQJX87VfLWR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}