SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da6049bacaa445d522d268a4f31f02f87ed228f39998cd5ca4c1d657f8e35323' 
  AND token = 'ZVBVAmygr0sKU5SOOKtdaQ0YkeiN6gw3WS6j7+lKi3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}