SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed3fd368ef4006ee6486c4d63ed76eb0662e48beb01d4860421b105a728c0a7' 
  AND token = 'BOAzxDbvfW3lSN1HlF/ByyhGRVHgkWASxEFtZ9wHqOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}