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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6daf2b4e3739d6ea03e52800d0c49ac3997ff09242737ee0773999884441d4cd' 
  AND token = 'PbJx/InAsWLWR5mMkPzX4lrLWgZCOdLoAFNU5gk4uPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}