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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e37f8659d78154f522446fcc16005c56941e3378e4f91114af4b7540cefb7a' 
  AND token = 'X7vJfOU3lNAe7guJlPH0NMtiWCb3K5Y1cX7xWOEpuHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}