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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46374da5c19e7384243a1d919a7710ccc2388bbc28fe126e2c1f866aca55567e' 
  AND token = '3kEOUYAh4tGXL/iSPDXOSd0VSfZY/c27X58OGU2JGKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}