SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09233ecf1d514e9adc98933926efdddcf0c255ab00ffdf2d75ca865514a76187' 
  AND token = 'Ius1Vv1KGoh/+6bLAN0D+i/aLGjuzDwmXZ4hCuyqoJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}