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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8189b8c029cc10320fd5e5ca4bac24fedffb933b6669f5232881941282b0b67f' 
  AND token = 'Mw3U4CvVqiYTjteuKVm4U2VAk6tIddwCEOdX0V+US6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}