SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da37ded0325a1e718e840c632aee531531b9ce081183653ce0ba15750207136f' 
  AND token = 'cz197M69aKxr69dbxjxsjSsnHWwX9SuwdG9JWbpMiz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}