SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ea13c1ce0b2875446a79a1a554b291d9a0e19d7d954a6cc2e1eb63bd8175099' 
  AND token = 'mSCOhNSoxGDF0nQshvgPQlCvYV5ZNu4OsObBOkFDBAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}