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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8c4d2bdedbbef889cac5acd9abf3e65216051af3bf2f25b99ccb0f50cc1cc25' 
  AND token = '7xUAd2rEQuoI0q2rJSd5lnGdOqNUKGOuSfvXFjKwU/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}