SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d09aba2acd68e1db96560e288f261e8d6b9eaeb529b69da6e77fe4ead6fb239' 
  AND token = 'JK0oLUH+NuIT3drRUV91ZGQVwxog3Eacl7df6y6Lb8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}