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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91e222b2294e48b32b49e2f78b6671d9d84e2e641f2328a4c6ffacba3038694f' 
  AND token = '+1/cEnMvbgnBU4iHiD3a/UJ0v8LYpSHBlKH1oqzAlQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}