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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f36494f9c2acf1849af86040e6f21174ab7d419c2b6e1836293ad8d32a3b942' 
  AND token = 'XXl9VBOFNpm4zdYT2HIr1WDYXJ3Y+pI5Qan0OG0g2Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}