SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4285fd8029ff1e10931db19d505b5d83cf44e30a11e03cc9affde118c11b29a' 
  AND token = 'a4hP6YHoc5BtcesQprgkQMcPYOuX7WT5Dl2jvrZq9lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}