SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165f19e69991180deee8c18bbf819607960abdb88cbfb19afed10e03ed23eaba' 
  AND token = '+eoY5O1y5Sce7MfzqgyEBbG2uWUbboMUbA2/PT/G4Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}