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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7845460e95fd6c7bc1f0e41bfab284fd7a89dacf57d12266129a52bca44e33c4' 
  AND token = 'rkPIIl0EDQLRLmeDk6kcPB43sR2CLfLk9Mf5av0eaK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}