SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e465e60ea9fb8fe3b81ca6c1dfcd5eaabe1c13f372d6e8ab649b5a8422a7ed8f' 
  AND token = 'dED+YL15bsYfcOpPjnZpI/lWeVu2SvFvkwi1j6piqd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}