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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f10fcbda969198f205e5ffe21c953cd254319f420e506ecfb6bcbfa96e0ed44' 
  AND token = 'MkCLDWnUgcDMRtD+obzJJ/3xWftu2cUmd0crwGZGij0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}