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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5450cf6c810d2c5a42df68bfee3b619155b84605751e385ac8ffa413de44dc40' 
  AND token = 'nMqedi8ESVtqUfeM4/paNvj3AIf8aHka8EwOosvgZjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}