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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654b2271fa7135bcd5308a31e377ee0ff1afbac4af0eb97b5f2ac90b97f27ac7' 
  AND token = 'vo/+/7RDITBeMRkplTyvAWqwvl5qe1ZMfqLDmC80v88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}