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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9044ec9a69c62f73b5bd3c7e224703a3d1b89680448211c0e6d06eed80865b78' 
  AND token = 'kKqDSGvx6ck2XYr3IufwFpUzTny00zvlDHN7srqopyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}