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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4286e66618009be67debc6f1fb0bdc6ab0d9e751153d319d8fbbe7bdb85fcc52' 
  AND token = '0k6GFaQ8MNNiWHyKdm0wdoFzblSs6DRgxef/ldcnHCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}