SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f209bd6f0f788f4e368a8972acbbe9559f82ee3e4effa004299d218078ff88f0' 
  AND token = 'lz/TgNDw3GqLKKMq694mQ1xM0q9lUb5HXY7mFjUsAzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}