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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae25d976b35e07afc4eb4082a5d4de603c044248d2785e01431dcfd6baea323' 
  AND token = 'EnC8tF8P/2JfG5EGe90AruRT7acwk9LW9KHAQu7duu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}