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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51ac584598bdbb77cc6474e7478da410f7cb6e195c387ff3d222ce7cf463b19f' 
  AND token = '+epcQuAHD4viy6QYThZtEHTQ0lE0vwfOCi7qGEbQE6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}