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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fce5628f9cb0bb9b7aa16eea8a84f219b21b9e90f418ba7c540cb2c52677447' 
  AND token = 'FVAAyd8vu+66E4KYYwI2AJwkHrhoRSJw1X2YMxa5RNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}