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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b7be615b9d231512791e16869e2634df8ce79b494a02e32443403ff002aefae' 
  AND token = 'XvIe0DWAAy9xYgi4T2UcUBnYtQeXNnaP6BBX97TniZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}