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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6396ec621a42a89b0d8ce6d644b8bfdc3f74fbf0a41542a92a609d8a820796' 
  AND token = 'lUlnBOXYoDj96Jv5u0qMMZ8cxlaMngDScmr8oPU5Iiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}