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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de13c6593e5e5c97132ce83483664b7a10e048dd0d8bda933bfab1f9237f369' 
  AND token = 'PTRasS5HzB+BYOmgBtVDVzHj9A0OsadW1oIRsPS30N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}