SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d8f4b4dc448de86892691c5f3539739fe3bf208cf9dfcede0d1bc86abdf2426' 
  AND token = '+TG5Wjzo6lpQPTtnrjAtn7+riw0hBZLqP7OgcpxXEWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}