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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f76beebc82d07689cb6a689c8ed7b87b7727691d3f8b52e44b399ca32e629879' 
  AND token = 'yekm1KvV9IAQKbgJGyKOXYw2YTKIr3i/GlGvWVGUFe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}