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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dff54821a2b820f8a992038185a58eab27617ef5ccb65f36a8dd0cd7e2002a3e' 
  AND token = 'GxWNTI/F8Y7h1GT0u6TRRfjuvGpzypJW/E6PHLeXjy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}