SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dc93e9195251eaf2e832e41926169758f75345058f2e5e78e9d3a82751a3040' 
  AND token = 'a5W1NS+2AV0AWDRwpQ9GtapRDvbxyHYlrFgkI7i0tl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}