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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c6d5df2ab831162326e16f45a73e9a6a69437d1c1e0f8d4eeaa97771978a318' 
  AND token = 'cboF+V0+S7jaA8fDmmPGnXP8GDmyWPqDvI0w8+E28Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}