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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74456c08b25b7408a676722b33da18a233d9cd4c4de5aecdc1d2d4f95d8d6176' 
  AND token = 'aViGInZEBiYvNp0Tn+IISItl2yU9biDWSkHNNwiijoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}