SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd221e8bc61d7260def14c79af7b8bbf55fab6e8fd501344568e64c564b5b7e5d' 
  AND token = '2Bz/edPeF0L2OKJF0i9wzGzGwC5DxRG6WD2u+090+Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}