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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c26ce1c3b2810ed24cdb9e817a288343ebceefd230bd6423b09a146bf9e3a7' 
  AND token = '32+GW98MnHUxWkXL89HQ0giTz4zToJyqM2fYsGTrCJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}