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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65d5d9efdba86df4372aca0c6c8305a340b56334a1424f0cf36092b87f00a9f' 
  AND token = 'U19Be8IfkEb5yengQtKDm1vyA1U976V0CjGvkS6oF4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}