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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f17acde1df15454e18b480e8f8a3f3f58401d964746da36101dd76e5ad66f9a8' 
  AND token = 'RuUMd90gqlGo5bY1E1xCPzjaTtr2OQhs9PVRMWNPWe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}