SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f11c8962e529d5d3093ef0209d3126185c48ede3615fc433e710b983cb63284' 
  AND token = 'LxP4/Uk8PFKw5uz8fxxNbcRhozeF1ykI5hLLFFJSq64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}