SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc645a95588b0a9545a90125bf61febfd2d14a22e02c811aa6fc1e0f28f33518' 
  AND token = 'A7xnYHZw9FNEHvimXoQxch4Oq30s3FPjVTmXCH0LYAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}