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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb8bbdc6a610e908a773af45a1c0ac1c868b44c126393b6a0907624e8c383e62' 
  AND token = '6QNEgDdMrK8aTL/PSlcAbIVahEIoinAr0cophNQzqvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}