SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19f4620588c87c657d0930dec17f436e1e718a74db8b45a5f5a29c76a6f2eb69' 
  AND token = 'HDVkchDDF87v0a6PPkUapId8r0KLDK2uA8StpoBrgFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}