SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d5c38e5259642f5b7dcd49e137dab972152b4dff5f54cf7bbe1c3d9a970bb22' 
  AND token = 's1W1s8jZAhFCOma+89Ju8vjb+3P2dsp4Jurh0tLK6bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}