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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a21375273f3dc4ea81b246e2ba28719e945bde8e681ae462747233d25f408e3' 
  AND token = '73RGyBtW4+ZNoXRjGYxa3QaTmMxn7O+bBcA7zzQ2U2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}