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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55c09cda9261795b90bf95eba7c437740e3971aabfd2d7788e7c536d2f9d6a54' 
  AND token = 'q61C4HN+Y9GVqT0mAcEZFgdksz7tn5Xe0OSznNUa1Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}